Abstract: The frame-core tube structure system is widely used in super high-rise buildings because of its large lateral stiffness, high bearing capacity and good seismic performance. Traditional core tube construction mostly adopts the "full climbing" construction method, and the vertical structure and horizontal structure construction are not synchronized, which not only affects the quality of core tube construction, but also may cause internal construction safety hazards. The purpose of this paper is to optimize the construction technology of core tube structure system in super high-rise buildings. Taking the B1-1A tower project of the Pearl River New City as an example, this paper compares the process characteristics, advantages and disadvantages of two construction technologies, namely "external climbing and internal supporting" and "full climbing", and discusses the key points of operation and management of core tube construction when using the "external climbing and internal supporting" technology. The research results show that compared with the "full climbing" construction technology, the construction method of "external climbing and internal supporting" has significant technical advancement, safety and economy; the construction of "external climbing and internal supporting" must strengthen the coordination between the inner and outer formwork to ensure that the construction of the core tube cylinder can be carried out in a safe and efficient way. In the construction of "external climbing and internal support", the connection between internal and external formwork must be strengthened to ensure the construction quality; the construction method of "external climbing and internal support" can adopt the method of installing separate unloading platform, which can be used as a material transfer station to cooperate with the material turnover and transportation.