Abstract: Accelerated urbanization has led to increasingly prominent issues related to the accumulation and inefficient treatment of construction waste, particularly waste bricks, which are difficult to utilize on a large scale in road base courses due to their low strength and high water absorption. Therefore, this study investigated the combination of waste bricks and concrete crushed stone as a primary material for pavement base courses, and systematically explored the feasibility of its resource utilization. Through mechanical performance tests, three mix proportions with different waste brick contents (0%, 30%, and 50%) were designed, and compaction tests along with 90-day unconfined compressive strength tests were conducted. The results indicated that as the waste brick content increased, the crushing value of the mixture rose from 21.5% to 32.15%, the optimum moisture content increased from 14.07% to 19.51%, and the maximum dry density decreased from 1.874 g/cm³ to 1.678 g/cm³. The 90-day unconfined compressive strength decreased from 10.17 MPa (without waste bricks) to 6.12 MPa (with 50% waste bricks). The mixture with 30% waste brick content still met the strength requirements for base courses of secondary and lower-grade highways. In summary, waste bricks can be used in road base courses, but their content should not exceed 30%, and further modification is necessary to enhance their performance.